Bioavailability of a Lipidic Formulation of Curcumin in Healthy Human Volunteers

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Bioavailability of a Lipidic Formulation of Curcumin in Healthy Human Volunteers

Numerous publications have reported the significant pharmacodynamic activity of Curcumin (CRM) despite low or undetectable levels in plasma. The objective of the present study was to perform a detailed pharmacokinetic evaluation of CRM after the oral administration of a highly bioavailable lipidic formulation of CRM (CRM-LF) in human subjects. Cmax, Tmax and AUC0-¥ were found to be 183.35 ± 37....

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ژورنال

عنوان ژورنال: Pharmaceutics

سال: 2012

ISSN: 1999-4923

DOI: 10.3390/pharmaceutics4040517